
Lower Arsnicker Keys Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to $1,045 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Lower Arsnicker Keys Hotel Deals

Chesapeake Beach Resort
83409 Overseas Hwy, Islamorada, FL
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $179 total per night from Oct 2 to Oct 3
$179 total
Oct 2 - Oct 3
Total with taxes and fees
9/10 Wonderful! (1,534 reviews)
"Everything was perfect and beautiful"
Reviewed on Sep 23, 2025

Cheeca Lodge & Spa
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $170 total per night from Oct 6 to Oct 7
$170 total
Oct 6 - Oct 7
Total with taxes and fees
9/10 Wonderful! (1,210 reviews)
"I love it"
Reviewed on Sep 21, 2025

Amara Cay Resort
80001 Overseas Hwy, Islamorada, FL
Fully refundableReserve now, pay when you stay
$223 nightly
The price is $251 total per night from Oct 1 to Oct 2
$251 total
Oct 1 - Oct 2
Total with taxes and fees
8.8/10 Excellent! (1,258 reviews)
"The resort had free kayaking and paddle boarding which was a great addition."
Reviewed on Sep 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More vacations you might like
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Layton Hotels
- Oceanfront Hotels in Layton
- Resorts & Hotels with Spas in Layton
- Motels in Layton
- Apartments in Layton
- Cheap Hotels in Layton
- Hotels on the River in Layton
- Beach Hotels in Layton
- Villas in Layton
- Condo Rentals in Layton
- Cottages in Layton
- Golf Hotels in Layton
- Luxury Hotels in Layton
- Resorts in Layton
- Hotels with a View in Layton
- Long Key Hotels
- Hotels near Long Key State Park
- Condo Rentals in Long Key
- Resorts in Long Key
- Beach Hotels in Long Key
- Hotels with Laundry Facilities in Long Key
- Equity Lifestyle Hotels in Long Key
- Apartments in Long Key
- Pet-friendly Hotels in Long Key
- Cheap Hotels in Long Key
- Cabin Rentals in Long Key
- Motels in Long Key
- Luxury Hotels in Long Key
- Resorts & Hotels with Spas in Long Key
- Cottages in Long Key
- RV Parks in Long Key
- Hotels on the River in Long Key
- Hotels with Restaurants in Long Key
- Hotel Wedding Venues Hotels in Long Key
- Hotels with Bars in Long Key
- Hotels & Resorts for Couples in Long Key
- Villas in Long Key
- Romantic Hotels in Long Key
- Hotels near Anne's Beach
- Hotels near Lower Matecumbe Beach
- Hotels near Sunset Drive Beach
- Lower Matecumbe Key Hotels
- RV Parks in Lower Matecumbe Key
- Lignumvitae Key Botanical State Park Hotels
- Cottages in Conch Key
- Conch Key Hotels
- Villas in Conch Key
- Resorts in Conch Key
- RV Parks in Conch Key
- Cabin Rentals in Conch Key
- Motels in Conch Key
- Pet-friendly Hotels in Conch Key
- Beach Hotels in Conch Key
- Houseboats in Conch Key
- Islamorada Hotels
- Hotels near Little Conch Key
- Hotels near Bud n' Mary's Dive Center
- Hotels near Matecumbe
- Duck Key Hotels
- Resorts in Duck Key
- Cheap Hotels in Duck Key
- Villas in Duck Key
- RV Parks in Duck Key
- 5 Star Hotels in Duck Key
- Houseboats in Duck Key
- Vacation Homes in Duck Key
- Hotels with Laundry Facilities in Duck Key
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.